所指示的分類、所代表的人稱、引導從句時可修飾的成分不同。Who指的是人，whose既可以指人，也可以指物。Who做主格，whose只能做賓格。Who引導的從句中，who只能代表人，而whose可修飾從句（定于從句）中的主語、賓語、介詞賓語等不同成分。

Whose的例句

I saw a man shouting at a driver whose car was blocking the street.

我看見一個男人正朝一個司機叫嚷，他的車把街道堵塞了。

Whose daughter is she?

她是誰的女兒？

I can't remember whose idea it was for us to meet again.

我記不清我們再次會面是誰的主意了。

Whose handwriting is this? Can you identify it?

這是誰的筆跡，你辨認得出來嗎？

Who的例句

Who's there?

誰在哪兒？

Police have not been able to find out who was responsible for the forgeries

警方還未能查明誰是這些造假案的元兇。

There are those who eat out for a special occasion, or treat themselves

有些人會在特殊的日子或犒勞自己時出去吃飯。

Who is the least popular man around here?

這里誰最不受歡迎？